Cancer Treatments & Oral Health

Most people are aware of common side effects of cancer treatment like nausea and hair loss. But many don’t realize that most people treated for cancer develop problems in the mouth. These problems can make it hard to eat, talk, and swallow. This may interfere with cancer treatment and lessen quality of life.


Head and neck radiation and chemotherapy can cause mouth problems that range from dry mouth to life-threatening infections.

For example, mouth sores can occur because chemotherapy and radiation kill fast-growing cells such as cancer cells. But these treatments also kill healthy cells that are fast-growing, like the cells that line your mouth. In addition, radiation to the head and neck can damage the glands that make saliva, or salivary glands, greatly reducing the amount of saliva that’s produced. Without enough saliva, tooth decay and other infections can develop.


Head and neck radiation may cause:

  • Dry mouth
  • Severe tooth decay
  • Loss of taste or changes in the way food tastes
  • Sore mouth and gums
  • Infections
  • Jaw stiffness
  • Jaw bone changes

Chemotherapy may cause:

  • Dry mouth
  • Painful mouth and gums
  • Change in taste
  • Burning, peeling, or swollen tongue
  • Infection
  • Mouth ulcers


Treatment will depend on which mouth problems you develop. For example, treatment for jaw stiffness or pain might consist of daily jaw exercises. Treatment for oral mucositis, which results in painful mouth sores, might require a medication to coat the lining of your mouth to protect it when you eat and/or a topical medication to numb the pain.

Be sure to follow all directions from your doctor or dentist about treating your mouth problems.